Delta Phi Omega Sorority, Inc. was established on December 6, 1998 at the University of Houston by sixteen South Asian women who recognized the need for an organization to promote the advancement of South Asian women. Sixteen women from various backgrounds came together with the common goal of uniting women among the South Asian community. The Founders created the backbone of this sorority on the basis of the five pillars of Sisterhood, Respect, Loyalty, Honesty, and Friendship. They envisioned an organization that would highlight the diverse Indian culture through participation in community and social service projects.

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Through determination and perseverance, this vision evolved into a reality and as a result has become the most sought after sorority for not only South Asian women, but women of all backgrounds across the United States. With each passing year, Delta Phi Omega continues to grow and make its presence known not only within their respective universities but also within the community. It is proud to be known as the nation's largest, strongest, and fastest-growing South Asian interest sorority. 

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Delta Phi Omega has expanded to include 22 chapters and 24 colonies. The women of Delta Phi Omega understand that only through hard work, optimism, and a pure vision will the notion of sisterhood among South Asians prevail.